Patient-centric multi-modal major depressive disorder detection
Sandura Shumba*; Johannes Coetzer
Major Depressive Disorder (MDD) remains a pressing global health issue, necessitating diagnostic models that effectively capture both neural and emotional cues. This study proposes a multi-modal framework that integrates generalised ...
The effectiveness and efficacy of stretching and proprioceptive neuromuscular facilitation on the context in spastic diplegic cerebral palsy children
Arup Kumar Borah*; Priyaka Goswami
Spasticity is a upper motor neuron disorder and can be seen in neurological conditions like and stroke and multiple sclerosis. Although the incidence rate of spasticity is unknown, it can put pressure on the health conditions
Combination of micronutrient mixture, probiotics, collagen peptides, omega 3, cannabidiol, and diet may reduce the risk of development and progression of Post-Traumatic Stress Disorder (PTSD), and improve its treatment
Kedar N Prasad*
Post-Traumatic Stress Disorder (PTSD) is a complex psychiatric disorder caused by sudden exposure to a single or repeated traumatic events. The major symptoms include flashbacks, nightmares, hyperarousal, depression, substance abuse, suicidal tendencies, impaired learning ability, and cognitive dysfunction.
The impact of Cognitive Reserve (CR) on the neuropsychological performance of pre-surgical patients with Temporal Lobe Epilepsy (TLE): A case series
Andrew D Lokai, PhD*; Evita Conway, MA; Heidi A Bender, PhD; Natalie Edman, MA; Jennifer Shum, MD; Padmaja Kandula, MD; Amanda Sacks-Zimmerman, PhD
Epilepsy, a condition characterized by recurrent and unprovoked seizures, is among the most commonly diagnosed chronic neurological disorders [1]. Seizures are excessive bursts of electrical activity generated within distinct cortical regions.
Mechanisms of delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage
M Daniela Orellana Zambrano; Takashi Kitani; Jason J Chang; Nitin Goyal*
The management of Aneurysmal Subarachnoid Hemorrhage (aSAH) in-volves monitoring with clinical exam, vital signs, and transcranial Doppler. “Delayed Cerebral Ischemia” (DCI) is characterized by clinical deterioration and evidence of stroke on imaging that occur beyond the first 72 hours after aSAH.
Integrative analysis of microRNA as blood-based biomarkers in amyotrophic lateral sclerosis
Shijie He; Yaoxinyi Hu; Fangfei Zhang*
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease with limited diagnostic and prognostic tools. The identification of minimally invasive biomarkers is critical for early diagnosis, monitoring disease progression, and evaluating therapeutic responses. MicroRNAs (miRNAs), small non-coding RNAs that regulate gene expression.
Risk of re-bleed in cases of aneurysmal subarachnoid hemorrhage upon external ventricular drain placement: Systematic review
Bader Ali*; Sarah Kawtharani; Elias Horanieh; Houssein Darwish
Aneurysmal Subarachnoid Hemorrhage (aSAH) requires immediate treatment which can lead to better patient outcomes. If acute hydrocephalus is present, a drain should be placed before securing the ruptured aneurysm due to the rapid and devastating outcomes of hydrocephalus.
Assessment of auditory perceptual functions in patients with Parkinson's disease
Sherifa Ahmed Hamed*; Mohamed Ahmed Abd-El Hamed; Amira Mohamed Oseily; Mohamed Kamal Sabra Mohamed
Hearing impairments are manifestations of Parkinson's Disease (PD). We aimed to assess Central Auditory Processing (CAP) functions with PD and their predictors. This was a cross-sectional study. It included 35 patients (male=21; female=14).
Personalized stress detection and reduction in elderly care homes using AI and wearable technology
Tanishk Prakash Dubey*; Amit Kumar Ahuja; BP Mishra; Komal Mishra; Gaurav Bhushan
Stress is a state of increased physical and psychological tension that can significantly affect an individual's health and well-being. Various physiological, psychological, environmental, and emotional factors contribute to stress, and poor management can lead to serious health consequences.
Rewiring the pituitary: Mechanistic insights into cellular flexibility and adaptation
Ribeiro Mariana*; Evangelista Victor
Pituitary cell plasticity has emerged as a critical concept in understanding the adaptability of endocrine function. Historically constrained by technical and conceptual limitations, early studies laid the foundation for identifying multipotential and multihormonal cell populations within the pituitary gland.
"Dancing fingers": A case report of nitrous oxide poisoning with rare upper extremity presentation
Jane Dalisay, DO; Yamandu Rodriguez, MD; Bertrand Liang, MD, PhD*
Nitrous oxide abuse is increasing globally particularly in the young, and manifests as neurologic symptoms typically affecting the lower extremities. We present a case of a patient with significant nitrous oxide abuse who presented with upper extremity symptoms of decreased sensation in the hand, with difficult to control spontaneous movement of the fingers bilaterally ("dancing fingers").
Lumbar neurofibroma: Etiology, clinical presentation, surgical indications, and surgical technique. A focused view about surgical experience in Viseu-Portugal
Marcel Şincari*; Margarida Conceição; Mark-Daniel Şincar
Lumbar neurofibroma is a benign neoplasm that originates from peripheral nerves, specifically from Schwann cells. While it can occur at various anatomical sites, its manifestation in the lumbar region has specific clinical and neurosurgical aspects, which are of great relevance for accurate diagnosis and effective treatment.
Cystic meningiomas, literature review and case reports: Nauta classification modification
Marcel Şincari*; Margarida Conceição; Mark-Daniel Şincari
Meningiomas of central nervous system are common lesion, but among them the cystic meningiomas are very rare tumors. We report two cases of cystic meningioma successfully treated and we propose the modification of the widely used Nauta classification of cystic meningiomas.
Cross-modal audio-visual rehabilitation in unilateral cochlear implanted patients: A pilot study
Francesco Lazzerini*; Luca Bruschini; Luca Baldassari; Francesca Forli; Stefano Berrettini
For many hearing-impaired individuals, even with the aid of Hearing Aids (HAs) or Cochlear Implants (CIs), one of the most demanding tasks remains understanding speech in noise, which is closely tied to spatial hearing. Recent research has highlighted the significant advantages of integrating information from various sensory modalities, a phenomenon known as cross-modal stimulation.